Levodopa-reduced Mucuna pruriens seed extract shows neuroprotective effects against Parkinson's disease in murine microglia and human neuroblastoma cells, Caenorhabditis elegans, and Drosophila melanogaster
Publication Year: 2018
Authors: Johnson S.L. et al.
Study Type: Preclinical — In vitro and invertebrate models
PMCID: PMC6164394 | Link: View on PubMed Central
Daily intake of Mucuna pruriens in advanced Parkinson's disease: a 16-week, noninferiority, randomised, crossover, pilot study
Journal: Movement Disorders
Publication Year: 2017
Authors: Cilia R. et al.
Study Type: Human — Randomized Crossover Pilot Study
PMID: 29352722 | Link: View on PubMed
Mucuna pruriens in Parkinson's disease: a double blind clinical and pharmacological study
Journal: Journal of Neurology, Neurosurgery and Psychiatry
Publication Year: 2004 | Volume: 75 | Issue: 12 | Pages: 1672–1677
Authors: Katzenschlager R. et al.
Study Type: Human — Randomized Double-Blind Crossover Trial
PMID: 15548480 | Link: View on PubMed
Network pharmacology and molecular docking analysis of Shankhpushpi against Alzheimer's and Parkinson's disease targets
Journal: Evidence-Based Complementary and Alternative Medicine
Publication Year: 2022
Authors: Hannan M.A. et al.
Study Type: Computational — In silico analysis
PMID: 36225186 | Link: View on PubMed
Convolvulus pluricaulis confers antidepressant and antioxidant effects via GABAergic and redox pathways
Publication Year: 2025
Study Type: Preclinical — In vivo (Drosophila)
PMCID: PMC12834108 | Link: View on PubMed Central
Nootropic, anxiolytic and CNS-depressant studies on different plant sources of Shankhpushpi
Journal: Pharmaceutical Biology
Publication Year: 2011 | Volume: 49 | Issue: 12 | Pages: 1234–1242
Authors: Malik J., Karan M., Vasisht K.
Study Type: Preclinical — In vivo (rodent)
DOI: 10.3109/13880209.2011.584539
Possible Involvement of Standardized Bacopa monniera Extract (CDRI-08) in Epigenetic Regulation of reelin and Brain-Derived Neurotrophic Factor to Enhance Memory
Journal: Frontiers in Pharmacology
Publication Year: 2016 | Volume: 7 | Article Number: 166
Authors: Jayakumar Preethi, Hemant K. Singh, Koilmani E. Rajan
Study Type: Preclinical — In vivo (rat)
PMID: 27445807 | PMCID: PMC4921742 | DOI: 10.3389/fphar.2016.00166
Neuroprotective and neurorescue action of Bacopa monnieri in MPTP-induced Parkinson's disease: an in-silico and in-vivo study
Journal: Frontiers in Pharmacology
Publication Year: 2021 | Volume: 12 | Article Number: 616413
Authors: Singh B. et al.
Study Type: Preclinical — In vivo (mouse) and in-silico
PMCID: PMC8007855 | Link: View on PubMed Central
Anti-Parkinsonian effects of Bacopa monnieri: insights from transgenic and pharmacological Caenorhabditis elegans models of Parkinson's disease
Journal: Biochemical and Biophysical Research Communications
Publication Year: 2011
Authors: Jadiya P. et al.
Study Type: Preclinical — In vivo (C. elegans)
PMID: 21784060 | Link: View on PubMed
A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults
Journal: Indian Journal of Psychological Medicine
Publication Year: 2012 | Volume: 34 | Issue: 3 | Pages: 255–262
Authors: Chandrasekhar K., Kapoor J., Anishetty S.
Study Type: Human — Randomized Controlled Trial
PMID: 23439798 | PMCID: PMC3573577 | Link: View on PubMed
Withania somnifera root extract improves catecholamines and physiological abnormalities in a Parkinson's disease model mouse
Journal: Journal of Ethnopharmacology
Publication Year: 2009 | Volume: 125 | Issue: 3 | Pages: 369–373
Authors: Rajasankar S. et al.
Study Type: Preclinical — In vivo (mouse)
PMID: 19666100 | Link: View on PubMed
Neuroprotective effects of Withania somnifera (KSM-66) root extract in the SH-SY5Y cell model of Parkinson's disease
Publication Year: 2021
Study Type: Preclinical — In vitro (SH-SY5Y cell model)
PMCID: PMC8569401 | Link: View on PubMed Central
Swarna Bhasma nanoparticles: characterization, antioxidant and immunomodulatory activity
Publication Year: 2025
Study Type: Preclinical — In vivo and physicochemical characterization
PMCID: PMC12309017 | Link: View on PubMed Central
Nanogold herbo-mineral formulation Neurogrit Gold attenuates 6-OHDA-induced dopaminergic neurodegeneration in a C. elegans model of Parkinson's disease
Publication Year: 2025
Study Type: Preclinical — In vivo (C. elegans)
PMCID: PMC12059624 | Link: View on PubMed Central
Neuroprotective effects of nanogold Ayurveda medicine Suvarna Bhasma against rotenone-induced Parkinson's-like model in zebrafish
Journal: Journal of Ayurveda and Integrative Medicine
Publication Year: 2023
Study Type: Preclinical — In vivo (zebrafish)
PMID: 38145607 | Link: View on PubMed
Possible Involvement of Standardized Bacopa monniera Extract (CDRI-08) in Epigenetic Regulation of reelin and Brain-Derived Neurotrophic Factor to Enhance Memory
Journal: Frontiers in Pharmacology
Publication Year: 2016 | Volume: 7 | Issue: No issue number listed | Article Number: 166
Authors: Jayakumar Preethi, Hemant K. Singh, Koilmani E. Rajan
PMID: 27445807 | PMCID: PMC4921742 | DOI: 10.3389/fphar.2016.00166
Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial
Journal: Phytotherapy Research
Publication Year: 2008 | Volume: 22 | Issue: 12 | Pages: 1629–1634
Authors: Con Stough, Luke A. Downey, Jenny Lloyd, Beata Silber, Stephanie Redman, Chris Hutchison, Keith Wesnes, Pradeep J. Nathan
PMID: 18683852 | DOI: 10.1002/ptr.2537
Bacopaside I alleviates depressive-like behaviors by modulating the gut microbiome and host metabolism in CUMS-induced mice
Journal: Biomedicine & Pharmacotherapy
Publication Year: 2024 | Volume: 170 | Issue: No issue number listed | Article Number: 115679
Authors: Jie Wang, Jiayun Xin, Xike Xu, Wei Chen, Yanhui Lv, Yanping Wei, Xintong Wei, Zhanhong Li, Qianqian Ding, Houyu Zhao, Yukun Wen, Xiuyun Zhang, Yiqun Fang, Xianpeng Zu
PMID: 38113632 | DOI: 10.1016/j.biopha.2023.115679
Assessment of bioavailability of gold bhasma in human participants: A pilot study
Journal: Journal of Ayurveda and Integrative Medicine
Publication Year: 2018 | Volume: 9 | Issue: 4 | Pages: 294–297
Authors: Trupti Patil-Bhole, Sangram Patil, Asmita A. Wele
PMID: 30459077 | DOI: 10.1016/j.jaim.2018.04.002
Comparative study on cellular entry of incinerated ancient gold particles (Swarna Bhasma) and chemically synthesized gold particles
Journal: Scientific Reports
Year: 2017 | Volume: 7 | Issue: 1 | Article Number: 10678
Authors: Daniel Beaudet, Simona Badilescu, Kiran Kuruvinashetti, Ahmad Sohrabi Kashani, Dilan Jaunky, Sylvie Ouellette, Alisa Piekny, Muthukumaran Packirisamy
PMID: 28878355 | DOI: 10.1038/s41598-017-10872-3
Ashwagandha Root Extract Stabilises Physiological Stress Responses in Male and Female Team Sports Athletes During Pre-Season Training
Journal: Nutrients
Publication Year: 2026 | Volume: 18 | Issue: 2 | Article Number: 230
Authors: Olivia C. Coope, Esteban Otaegui, Manolo Suárez, Alex Levington, Maria Abad-Sangrà, Beth Lloyd, Tilly J. Spurr, Blanca Roman-Viñas
PMID: 41599843 | DOI: 10.3390/nu18020230
Neuritic regeneration and synaptic reconstruction induced by withanolide A
Journal: British Journal of Pharmacology
Authors: Tomoharu Kuboyama, Chihiro Tohda, Katsuko Komatsu
PMID: 15711595 | PMCID: PMC1576076 | DOI: 10.1038/sj.bjp.0706122
Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study
Journal: Journal of Ethnopharmacology
Publication Year: 2021 | Volume: 264 | Article Number: 113276
Authors: Langade D. et al.
PMID: 32818573